Probing channel, pump, and transporter function using single-molecule fluorescence.

10.1002/9781119085126.ch11


Our chapter in Pumps, Channels, and Transporters.

The ability of patch clamping to monitor individual ion channels revolutionized our approach to understanding the discrete functional states of these membrane proteins, including how ligands, point mutations, and the electrochemical potential affect channel function.

Probing channel, pump, and transporter function using single-molecule fluorescence. - May 10, 2015 - Mark Wallace